Pitx3eyl
|
HMGU
|
FACS (GMC) / leukocytes (FSC/SSC) /Gr1+ CD11b+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0165
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
162f:132m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
FACS (GMC) / leukocytes (FSC/SSC) /CD3+ 8+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0359
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Bulging eye
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
FACS (GMC) / leukocytes (FSC/SSC) /CD3+ 4+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0682
|
Successful |
Pitx3eyl
|
HMGU
|
FACS (GMC) / leukocytes (FSC/SSC) /gamma delta TCR+CD3+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.219
|
Successful |
Pitx3eyl
|
HMGU
|
FACS (GMC) / leukocytes (FSC/SSC) /CD3- DX5+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.651
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Iris/Pupil
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Cartilage tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Striatum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Kyphosis
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Lumbar processes
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
8f:6m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Corneal deposits
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Fibula
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Shape of vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
5f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0495
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Peyers Patch
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Small Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Lens Opacity
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
FACS (GMC) / CD19+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.730
|
Successful |
Pitx3eyl
|
HMGU
|
FACS (GMC) / leukocytes (FSC/SSC) /CD3+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0824
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Thalamus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
FACS (GMC) / CD19+/CD5+
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.368
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Lymph Node
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0857
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.06×10-32
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Zygomatic bone
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.242
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Shape of ribs
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Time Partition
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.000817
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Boli
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0564
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Familiar object exploration percentage
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.154
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Time on Board
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.517
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Latency grooming
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.414
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
4.16×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Unfamiliar object exploration number
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0135
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Latency familiar object exploration
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.000244
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Unfamiliar object exploration percentage
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0267
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Familiar object exploration number
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
9.52×10-06
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Body weight
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Latency unfamiliar object exploration
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.00348
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0846
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HOM
|
6f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
2.84×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.100
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
5f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0314
|
Successful |
Pitx3eyl
|
HMGU
|
Slit lamp 2 (GMC) / Slit lamp description
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Ferritin
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.128
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / C-Reactive protein
|
HOM
|
5f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00939
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Transferrin
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.106
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / ST
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.38×10-06
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Lipase activity
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.489
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Corneal vascularization
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000589
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Thymus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / Body weight
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Skeletal Muscle
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / f-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / age
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / MV-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / TV-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Position
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / PEF-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / PIF-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Peripheral Nervous System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Scoliosis
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Vesicular Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
3.55×10-07
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / pNN5(6>ms)
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Mammary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Fusion of vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Tibia
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Iris transilumination
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
7.44×10-14
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.589
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Percentage monocytes retested
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.674
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Percentage granulocytes
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.150
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Percentage eosinophiles
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.534
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Absolute number of monocytes
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.392
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Absolute number of granulocytes
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.360
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Adrenal gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Absolute number of eosinophiles
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.652
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Percentage lymphocytes
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0928
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Lens
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / QTc
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0118
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Body position
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.277
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Tremor
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Body weight
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000274
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000589
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Locomotive Activity
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.213
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Alive
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.318
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0777
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Hematocrit
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.386
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Mean corpuscular volume
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.472
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Mean corpuscular hemoglobin
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.320
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Mean corpuscular hemoglobin concentration
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.151
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / White blood cell
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.536
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Red blood cell
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.431
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Platelet
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00101
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Trachea
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Hemoglobin
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.685
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Persistence of hyaloid vascular system
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.705
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Distribution index of red blood cells
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.724
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Cerebral Cortex
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Processes on vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Eye
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.21×10-37
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0461
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Maxilla/Pre-maxilla
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Mean platelets volume
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0958
|
Successful |
Pitx3eyl
|
HMGU
|
Haematology (GMC) / Absolute number of lymphocytes
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.853
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Testis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Kidney
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Caudal processes
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Pinna reflex
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Corneal Reflex
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Pituitary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Trunk Curl
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Limb grasping
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0775
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Vocalisation
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / rMSSD
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.814
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Retina
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Contact Righting Reflex
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Evidence of Biting
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Righting Reflex
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Transition
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena permanence
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / PR
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0347
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0768
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Urinary bladder
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Defecation
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.212
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Whiskers
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Lacrimation
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Olfactory Lobe
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Palpebral Closure
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.719
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Coat appeareance
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Positional Passivity
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Skin Color
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Bodyweight (GMC) / Bodyweight
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
2.12×10-06
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Tail Elevation
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Touch Escape
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Transfer Arousal
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0761
|
Successful |
Pitx3eyl
|
HMGU
|
Shirpa (GMC) / Gait
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.887
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Femur
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.27×10-06
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Cornea
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
5f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.00757
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
5.87×10-07
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.840
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.512
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Iris Pigmentation
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Grip Strength (GMC) / Forelimb grip strength measurement-t1
|
HOM
|
35f:60m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Grip Strength (GMC) / Body weight
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000274
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Thoracic processes
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Humerus
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Cerebellum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / Mean R amplitude
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Lordosis
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Ulna
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Sacral processes
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000494
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.935
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0411
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Vascular System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Retinal Pigmentation
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Line crossings
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
5.09×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Body weight
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
2.12×10-06
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Data confidence level
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Stretched attends
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0125
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Liver
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Holes explored
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0320
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Stomach
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Immobility
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Entries on Board
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.203
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Rearings box
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
4.05×10-08
|
Successful |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Rearings board
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Holes visited
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Holeboard (GMC) / Latency first hole exploration
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.451
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Hippocampus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.47×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Fat Mass (excluding skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0969
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Fertility of Homozygous Knock-out Mice / Gross Findings Female
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Lean Mass (excluding skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.114
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Bone Area (excluding skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.214
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Bone Mineral Density (excluding skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.785
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Skull shape
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Spinal cord
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / QRS
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.669
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Bone Mineral Content (including skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
6.12×10-06
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Bone Area (including skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
3.25×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
8f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.534
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Body length
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000258
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.450
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Body weight
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
2.40×10-07
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Corneal opacity
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Prostate gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Shape of ribcage
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Bone Mineral Content (excluding skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.153
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Lean Mass (including skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.120
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Fat Mass (including skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0899
|
Successful |
Pitx3eyl
|
HMGU
|
pDexa (GMC) / Bone Mineral Density (including skull)
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0906
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.761
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / RR
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000686
|
Successful |
Pitx3eyl
|
HMGU
|
Rotarod A (GMC) / Latency to fall - t1
|
HOM
|
28f:48m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Rotarod A (GMC) / Body weight
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Radius
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:28m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Brachydactyly
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Test duration
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0775
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Scapulae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Retinal Structure
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Skin
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Esophagus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Retina (combined)
|
HOM
|
1f:m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Heart Weight / Body weight
|
HOM
|
8f:6m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Pancreas
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Polysyndactylism
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Hypothalamus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Allergy (GMC) / Immunoglobulin E
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.532
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Dilation
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.640
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
5.36×10-10
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Eye
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
5f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0595
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000165
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / Mean SR amplitude
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Thyroid gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
f:2m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
8f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.000324
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Clavicle
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
ELISA (GMC) / IgG3
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
1.76×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
ELISA (GMC) / IgG1
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.668
|
Successful |
Pitx3eyl
|
HMGU
|
ELISA (GMC) / IgG2b
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.278
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Weight / Body weight curve
|
HOM
|
139f:118m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Body Weight / Body weight curve
|
HOM
|
61f:96m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
ELISA (GMC) / IgG2a
|
HOM
|
f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.454
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
1.09×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / PQ
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0345
|
Successful |
Pitx3eyl
|
HMGU
|
ELISA (GMC) / IgM
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0296
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Heart
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Epididymis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Digit integrity
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0135
|
Successful |
Pitx3eyl
|
HMGU
|
ERG (Electroretinogram) (GMC) / Body weight at ERG examination
|
HOM
|
7f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
4.13×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Eyelid closure
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Oviduct
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0421
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:28m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
ELISA (GMC) / IgA
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.640
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Aorta
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Syndactylism
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Vitreous
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Food efficiency (GMC) / Feces production
|
HOM
|
12f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0297
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
30f:25m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Food efficiency (GMC) / Food consumption
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.323
|
Successful |
Pitx3eyl
|
HMGU
|
Food efficiency (GMC) / Energy content of feces
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.426
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Narrow eye opening
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Heart Weight / Heart weight
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.00106
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00779
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.570
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / QTc Dispersion
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
40f:35m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Fertility of Homozygous Knock-out Mice / Gross Findings Male
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Cervical processes
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Food efficiency (GMC) / Body temperature rectal
|
HOM
|
12f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
2.76×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
Food efficiency (GMC) / Body weight
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
6.34×10-06
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Comment on XRay image
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / Comment
|
HOM
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / Comment
|
HOM
|
f:2m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000165
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.661
|
Successful |
Pitx3eyl
|
HMGU
|
Nociception Hotplate (GMC) / jumping
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Nociception Hotplate (GMC) / hind paw licking
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
3.48×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
Nociception Hotplate (GMC) / hind paw shaking
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.716
|
Successful |
Pitx3eyl
|
HMGU
|
Nociception Hotplate (GMC) / Body weight
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
1.06×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Synechia
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
5f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.126
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0857
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / HR
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
7.08×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.296
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Transitional vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Pelvis
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Lung
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Eyelid morphology
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Shape of spine
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Spleen
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
ERG (Electroretinogram) (GMC) / Comment on the ERG examination
|
HOM
|
7f:12m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:21m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Lower Urinary Tract
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Ovary
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.139
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / HRV
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.995
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Retinal Blood Vessels
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
8f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.567
|
Successful |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / Te-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / Ti-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Uterus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Mandibles
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.49×10-08
|
Successful |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / Ti/TT-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / MEF-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / MIF-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / sMV-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / sTV-active
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HOM
|
6f:5m
|
Linear Mixed Model framework, LME, including Weight
|
6.97×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
Spontaneous breathing (GMC) / mean-f
|
HOM
|
f:3m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Brainstem
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Alanine aminotransferase
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.979
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Aspartate aminotransferase
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0641
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Alpha-amylase
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00193
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Alkaline phosphatase
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00631
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Triglyceride
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
1.13×10-05
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Total cholesterol
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00174
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Corneal Sclerization
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Midbrain
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.733
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Uric acid
|
HOM
|
6f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00744
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Creatine kinase
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.230
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Teeth
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Submandibular Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Calcium
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.462
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / White Adipose Tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Weight / Body weight
|
HOM
|
113f:96m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Fusion between cornea and lens
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Glucose
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.135
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Creatinine
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.178
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Urea
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0836
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Potassium
|
HOM
|
5f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.155
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Sodium
|
HOM
|
5f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.162
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Total protein
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.245
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Chloride
|
HOM
|
5f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.286
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.36×10-08
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Electrocardiogram (ECG) / CV
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.850
|
Successful |
Pitx3eyl
|
HMGU
|
Clinical chemistry (GMC) / Phosphorus
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0978
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Fusion of ribs
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.152
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Brown adipose tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.07×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Retinal Blood Vessels Structure
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Body Weight / General comments about the mouse
|
HOM
|
20f:23m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Joints
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:21m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Large Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Climbing
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
X-ray / Fusion of processes
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Adult LacZ / Brain
|
HET
|
1f:1m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HOM
|
6f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
6.08×10-05
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
1.27×10-09
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pitx3tm1.1(KOMP)Vlcg
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |