Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Distance travelled - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.469
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Periphery permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.511
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / BN startle magnitude
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.722
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E12.5 / Forebrain morphology
|
HET
|
7f:11m
|
Supplied as data
|
1.00
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Number of centre entries
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.416
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Latency to centre entry
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.656
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP2 + pulse startle magnitude
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.315
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP3 + pulse startle magnitude
|
HET
|
12f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.254
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / 110dB startle magnitude
|
HET
|
12f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.563
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP1 + pulse startle magnitude
|
HET
|
12f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.431
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP3 startle magnitude
|
HET
|
12f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.773
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP4 startle magnitude
|
HET
|
12f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.830
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0480
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP1 startle magnitude
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.460
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP2 startle magnitude
|
HET
|
12f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.297
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E9.5 / Midbrain
|
HOM
|
1f:1m
|
Supplied as data
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Number of Rears
|
HET
|
32f:32m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Periphery distance travelled
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.229
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Center permanence time
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.326
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Indirect ophthalmoscopy / Right optic disc
|
HET
|
14f:6m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Grip-Strength / Forelimb grip strength measurement
|
HET
|
45f:18m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Grip-Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
45f:18m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.136
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E9.5 / Forebrain
|
HOM
|
1f:1m
|
Supplied as data
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.675
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.142
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Rotarod / Passive rotation
|
HET
|
45f:18m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Rotarod / Latency to fall
|
HET
|
45f:18m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Trunk curl
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Touch escape
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Startle response
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
0.147
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.605
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Corneal reflex
|
HET
|
15f:6m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Pinna reflex
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
0.356
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Limb grasping
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
0.0438
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Vocalisation
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
0.0756
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Contact righting reflex
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
0.359
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Center distance travelled
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0554
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E9.5 / Hindbrain
|
HOM
|
1f:1m
|
Supplied as data
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Tremor
|
HET
|
15f:6m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Gait
|
HET
|
13f:6m
|
Fisher Exact Test framework
|
0.0402
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Locomotor activity
|
HET
|
15f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.601
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Transfer arousal
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
0.0110
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E12.5 / Midbrain morphology
|
HET
|
7f:11m
|
Supplied as data
|
1.00
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Tail elevation
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
0.0186
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / Global prepulse inhibition
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0624
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / Prepulse inhibition - PP3
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.429
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / Prepulse inhibition - PP4
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.232
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Grip-Strength / Forelimb grip strength measurement mean
|
HET
|
15f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.939
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Grip-Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
15f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.386
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Number of rears - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0478
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Grip-Strength / Forelimb grip strength normalised against body weight
|
HET
|
15f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.224
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Grip-Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
15f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.655
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E12.5 / Neural Tube Closure
|
HET
|
7f:11m
|
Supplied as data
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Distance travelled
|
HET
|
32f:32m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Indirect ophthalmoscopy / Left optic disc
|
HET
|
14f:6m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Modified SHIRPA / Body position
|
HET
|
15f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E12.5 / Hindbrain morphology
|
HET
|
7f:11m
|
Supplied as data
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Slit Lamp / Iris/pupil light response
|
HET
|
14f:6m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0911
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Periphery average speed
|
HET
|
12f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.204
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Periphery permanence time
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.880
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Periphery resting time
|
HET
|
12f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.141
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / PP4 + pulse startle magnitude
|
HET
|
12f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.259
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Periphery distance travelled
|
HET
|
12f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.215
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Whole arena average speed
|
HET
|
12f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.203
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Whole arena resting time
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.351
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Whole arena permanence time
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.419
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Whole arena resting time
|
HET
|
12f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.0381
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Gross Morphology Embryo E9.5 / Neural tube closure
|
HOM
|
1f:1m
|
Supplied as data
|
1.00
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0561
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.706
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Open-field / Centre average speed
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.866
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Centre permanence time
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.674
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Centre resting time
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.598
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Open-field / Centre distance travelled
|
HET
|
12f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.896
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Hot Plate / Time of first response
|
HET
|
14f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.442
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Hot Plate / Type of response
|
HET
|
14f:6m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / Prepulse inhibition - PP1
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.157
|
Successful |
Smotm1Amc
|
MRC Harwell
|
Acoustic Startle&PPI / Prepulse inhibition - PP2
|
HET
|
12f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.110
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.142
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.376
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1b(KOMP)Wtsi
|
BCM
|
Open Field - centre start / Whole arena average speed
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.976
|
Successful |
Smotm1b(KOMP)Wtsi
|
BCM
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
8f:8m
|
|
|
NotProcessed |
Smotm1Amc
|
MRC Harwell
|
Open-field / Distance travelled
|
HET
|
48f:8m
|
|
|
NotProcessed |