Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Tremor
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
0.0377
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Tremor
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
0.0385
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Gait
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
0.132
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Gait
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Locomotor activity
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.585
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Locomotor activity
|
HET
|
1f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.887
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Transfer arousal
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Transfer arousal
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Global prepulse inhibition
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Global prepulse inhibition
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0167
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Tail elevation
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
0.367
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Tail elevation
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
0.397
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP3
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP3
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.00143
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement mean
|
HET
|
1f:2m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement mean
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.311
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP4
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP4
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.284
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
1f:2m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.146
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb grip strength normalised against body weight
|
HET
|
1f:2m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb grip strength normalised against body weight
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.162
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
1f:2m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.860
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / BN startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / BN startle magnitude
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.574
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Number of centre entries
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0296
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Number of centre entries
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.602
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Latency to centre entry
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.810
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Latency to centre entry
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.963
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP2 + pulse startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP2 + pulse startle magnitude
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0127
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP3 + pulse startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP3 + pulse startle magnitude
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.00339
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / 110dB startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / 110dB startle magnitude
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000877
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP1 + pulse startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP1 + pulse startle magnitude
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00538
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP3 startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP3 startle magnitude
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.517
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP4 startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP4 startle magnitude
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.429
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP1 startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP1 startle magnitude
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.611
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP2 startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP2 startle magnitude
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.456
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Body position
|
HET
|
1f:12m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Body position
|
HOM
|
14f:10m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery average speed
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0665
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery average speed
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0668
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery permanence time
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0881
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery permanence time
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.601
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP4 + pulse startle magnitude
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / PP4 + pulse startle magnitude
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0829
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery resting time
|
HET
|
1f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.545
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery resting time
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.872
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery distance travelled
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00435
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Periphery distance travelled
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.179
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Whole arena average speed
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0148
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Whole arena average speed
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0417
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Whole arena permanence time
|
HET
|
1f:12m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Whole arena permanence time
|
HOM
|
14f:10m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Whole arena resting time
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0598
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Whole arena resting time
|
HET
|
1f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.821
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement
|
HOM
|
42f:30m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement
|
HET
|
3f:6m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
42f:30m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
3f:6m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre average speed
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.465
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre average speed
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.830
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre permanence time
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.513
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre permanence time
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.601
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre resting time
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.263
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre resting time
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.591
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre distance travelled
|
HOM
|
14f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.505
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Open-field / Centre distance travelled
|
HET
|
1f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.524
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Hot Plate / Time of first response
|
HOM
|
14f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00145
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Hot Plate / Time of first response
|
HET
|
1f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.292
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Hot Plate / Type of response
|
HET
|
1f:12m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Hot Plate / Type of response
|
HOM
|
14f:10m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Rotarod / Passive rotation
|
HET
|
3f:36m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Rotarod / Passive rotation
|
HOM
|
42f:30m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Rotarod / Latency to fall
|
HOM
|
42f:30m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Rotarod / Latency to fall
|
HET
|
3f:36m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP1
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP1
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0193
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Trunk curl
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Trunk curl
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP2
|
HET
|
1f:1m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP2
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0983
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Touch escape
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Touch escape
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Startle response
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
0.00490
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Startle response
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
0.0384
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Corneal reflex
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Corneal reflex
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Pinna reflex
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
0.576
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Pinna reflex
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Limb grasping
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
0.655
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Limb grasping
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
0.750
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HET
|
274f:m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
811f:802m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Calorimetry / Ambulatory activity (no. of beam cuts)
|
HET
|
274f:m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
811f:802m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Vocalisation
|
HET
|
1f:12m
|
Fisher Exact Test framework
|
0.0430
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Vocalisation
|
HOM
|
14f:10m
|
Fisher Exact Test framework
|
0.528
|
Successful |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Contact righting reflex
|
HET
|
1f:12m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Modified SHIRPA / Contact righting reflex
|
HOM
|
14f:10m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Number of rears
|
HET
|
4f:48m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Number of rears
|
HOM
|
56f:40m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Distance travelled
|
HET
|
4f:48m
|
|
|
NotProcessed |
Akt2tm1Wcs
|
WTSI
|
Open-field / Distance travelled
|
HOM
|
56f:40m
|
|
|
NotProcessed |