All nervous system phenotype, behavior/neurological phenotype data for Dnase1

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Center permanence time HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.64774 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena resting time HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.40521 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.63105 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Center average speed HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.77217 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Contact righting HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Distance travelled - total HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.058417 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Number of rears - total HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.8138E-05 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery permanence time HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.64685 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Gait HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Percentage center time HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.64774 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Aggression HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.30660 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery average speed HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.039678 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HOM 7f:7m Fisher Exact Test framework 0.61961 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena average speed HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.058417 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Center distance travelled HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.79902 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Vocalization HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery distance travelled HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.020173 Success
Dnase1tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.70062 Success

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