Disease: Pfeiffer Syndrome

Name Pfeiffer Syndrome

Synonyms ACROCEPHALOSYNDACTYLY, TYPE V; ACS5;; ACS V;; NOACK SYNDROME , CRANIOFACIAL-SKELETAL-DERMATOLOGIC DYSPLASIA, INCLUDED

Locus 10q26.13

Associated Human Genes FGFR2 , FGFR1

Mouse Orthologs Fgfr2 , Fgfr1

Source OMIM:101600

Mouse Models associated by gene orthology

Mouse Gene Symbol Disease Gene Ortholog MGIPhenotype Similarity Score IMPCPhenotype Similarity Score
Fgfr2 FGFR2 77.65
Fgfr1 FGFR1 61.92 30.04

Potential Mouse Models predicted by phenotypic similarity

Mouse Gene Symbol In Disease Locus MGIPhenotype Similarity Score IMPCPhenotype Similarity Score
Lmna 73.12
Chst11 69.06
Satb2 68.72
Mmp2 67.97
Prdm16 66.45
Nfix 65.46
Tbx22 65.25
Pfas 64.58
Schip1 64.57
Cdo1 64.15
Arid5b 63.79
Alx1 63.55
Ulk4 61.97
Aldh1a3 61.63
Nme5 60.39
Kif27 60.37
Myo10 53.42 53.91
Mogs 48.25
C1ra 44.49